Dosedependent effect of smoking on risk of coronary heart. Engineering leaders must also ensure their teams work aligns with the goals of the business and that they keep one eye on the future so that theyre ready to scale and tackle the challenges that rapid growth creates. Development goal 4 to reduce mortality in children development, and chronic disease. The aim of this study was to assess the potential dosedependent effects of smoking on the risk of chd, heart failure and stroke in individuals with type 1 diabetes. Two distinct patterns of sweet taste liking have been described. We used multivariable logbinomial models gathered from 7120 young women in the longitudinal cohort known as the growing up today study to examine the following potential teen pregnancy risk factors. Objective dietary protein is an important modulator of glucose metabolism. View the profiles of people named daniel spiegelman. Chris spiegelman is the current national client group leader for the alternative investment funds practice at andersen. Semantic scholar profile for donna spiegelman, with 2467 highly influential citations and 795 scientific research papers. Nicola orsini, unit of nutritional epidemiology and unit of biostatistics, institute of environmental medicine, karolinska institutet, p. Join facebook to connect with daniel spiegelman and others you may know. The primary exposures included weight change from early adulthood age 18 years for women, 21 years for men to baseline enrollment median age 43 years for women, 52 years for men, and from baseline.
Teen pregnancy risk factors among young women of diverse. In 1986, participants were asked the following two questions. Jun 23, 2017 insulinlike growth factor 1 igf1 is associated with cardiovascular disease, itself a risk factor for hearing impairment, and, in animal studies, molecular evidence suggests a role for igf1 in. Premature delivery, a significant cause of child mortality and morbidity worldwide, is particularly prevalent in the developing world. The award was created in 1970 by the applied public health statistics section of the american public health association apha to honor a statistician, 40 years of age or younger, who has made outstanding contributions to health statistics, especially public health statistics. Objectives this study sought to examine associations between plantbased diet indices and chd incidence. May 01, 2017 donna spiegelman harvard university measurement error. Hsph professor donna spiegelman wins directors pioneer. Development and validation of a quantitative choline food. The cholineqffq food item list was developed by a panel of three nutrition experts in the division of human nutrition, university of cape town, including m.
Chan school of public health donna spiegelman software %lgtphcurv9. Healthful and unhealthful plantbased diets and the risk. Healthful dietary patterns and type 2 diabetes mellitus risk. One of 10 researchers honored, spiegelman is believed to be the first epidemiologist and biostatistician, and the first faculty member from a school of public health, to receive the award. Nutritional status and other baseline predictors of mortality. Augmented pseudolikelihood estimation for twophase.
Lauren m kunz, sharonlise t normand, molin wang, donna spiegelman, a maximum likelihood approach to power calculations for stepped wedge designs of binary outcomes, biostatistics. Participants 72 394 women who reported having one or more pregnancies that lasted at least six months, 3296 of whom had. Donna spiegelman, professor of epidemiologic methods at harvard school of public health hsph, has received a directors pioneer award from the national institutes of health nih. How often your midday meals were prepared at home and how often your evening meals were prepared at home, with five prespecified response categories in the nhs never, 12, 34, 56, and 7 timesweek and four categories in hpfs never, 12, 34, and 57 times. Implementation science definitions the scientific study of programs and interventions which promote the systematic uptake of clinical research findings and other evidencebased approaches into routine clinical practice and public health policy, hence improving the quality effectiveness, reliability, safety, appropriateness, equity, efficiency of health care. Novel insights into intimal hyperplasia in cardiac allograft vasculopathy. The answer, if youre harvards donna spiegelman, is you switch gears to become more actively involved in developing methods to better assure the. Bruce spiegelman honored for metabolic disease research. Daniel spiegelman software development engineer ii at amazon greater new york city area internet 1 person has recommended daniel. Impact of phthalate and bpa exposure during in utero. Donna spiegelman will be presenting her poster power calculations for stepped wedge designs with binary outcomes, in. The primary exposures included weight change from early adulthood age 18 years for women, 21 years for men to baseline enrollment median age 43 years for women, 52 years for men, and from baseline to.
Among sexual minorities, we also examined the following. How to build a great software development team built in. Consumption of meals prepared at home and risk of type 2. Chan school of public health, 677 huntington ave, kresge building room 802, boston, ma 02115 e. We used cox proportional hazards models to examine the. During my phd, i spent three months in boston at the harvard t. Building a great software development team takes more than finding the best developers. One of 10 researchers honored, spiegelman is believed to be the first epidemiologist and biostatistician, and the first faculty member from a school of public. Chan school of public health under the supervision of prof. View connor spiegelman s business profile as inside sales at carbon lounge.
Fuller lecture donna spiegelman department of statistics. Harvard selfdisclosed the case, involving donna spiegelman, a professor emerita of epidemiologic methods, in 2016. Sep 18, 2018 the aim of this study was to assess the potential dosedependent effects of smoking on the risk of chd, heart failure and stroke in individuals with type 1 diabetes. Phthalates and bisphenol a bpa are endocrine disrupting chemicals edcs that are widely used in a range of consumer products, resulting in ubiquitous human exposure 2,3,4. Oct 09, 2014 donna spiegelman, professor of epidemiologic methods at harvard school of public health hsph, has received a directors pioneer award from the national institutes of health nih.
Research design and methods our study included 21,457 singleton pregnancies reported among 15,294 participants of the nurses health study ii. Tobias et al quantified adherence to healthy diet patterns among 44 women at high risk for t2dm and report the results of a 16year followup. Research design and methods our study included 21,457 singleton pregnancies reported among 15,294 participants of the nurses health. Hpc system software enhanced by source code analysis. Find contacts direct phone number, email address, work history, and more. A read is counted each time someone views a publication summary such as the title, abstract, and list of authors, clicks on a figure, or views or downloads the fulltext. Objective we evaluated the associations of both maternal and paternal smoking during pregnancy with the risk of type 2 diabetes in daughters and explored whether any association was explained by weight at birth or bmi throughout life.
They develop and maintain a suite of homegrown software applications, oracle databases, java applications, the laboratory information management system, survey development apps, and web sites. Par has been defined as a marker of lung cancer risk in a prospective cohort study, but analysis of a larger numbers of cases are needed to deepen the significance of this study. Insulinlike growth factor 1 in relation to future hearing. Cohort studies of fat intake and the risk of breast cancer. Methods we included 73,710 women in nhs nurses health study 1984 to 2012, 92,329 women in nhs2 1991. These findings in the trend of mortality were consistent with the findings from other studies in both low and middleincome countries, 3,4,9, 16 although the mortality rate was slightly higher than the mortality rate of 8.
Healthful and unhealthful plantbased diets and the risk of. Most notably, yp created an award specifically to recognize spiegelmans unparalleled performance in the areas of leadership, culture and voice entitled, the lava award. Jun 21, 2017 phthalates and bpa are endocrine disrupting chemicals edcs widely used in consumer products. Debashis ghosh has been awarded the 20 mortimer spiegelman award. View connor spiegelmans business profile as inside sales at carbon lounge. Donna spiegelman was appointed the susan dwight bliss professor of biostatistics at the yale school of public health in 2018. Spiegelman, journal of the royal statistical society, series c, applied statistics, volume 67, part 2 2018, pages 307327.
In a new video, niehs grantee donna spiegelman, sc. However, not all plant foods are necessarily beneficial for health. Participants 72 394 women who reported having one or more pregnancies that lasted at least six months, 3296 of whom had laparoscopically. The study included 4506 individuals with type 1 diabetes who were participating in the finnish diabetic nephropathy finndiane study. Impact of estimated liver volume and liver weight on. A maximum likelihood approach to power calculations for stepped wedge designs of binary outcomes xin zhou department of epidemiology and biostatistics, harvard t. Origin, methods, and evolution of the three nurses health. Nih award winner spiegelman the epidemiology monitor. May 06, 20 debashis ghosh has been awarded the 20 mortimer spiegelman award. A team of 35 data management experts, programmers, application developers, and information technology specialists oversee daily operations. A maximum likelihood approach to power calculations for stepped wedge designs of binary outcomes.
Such a toolkit might include user friendly software or macros that might allow analysts to assess different scenarios for steppedwedge designs or different approaches to calculating costeffectiveness. In a series of discoveries, he showed that fat tissue secretes hormones, identified ppar. Healthful dietary patterns and type 2 diabetes mellitus. Research design and methods we used data from 34,453 participants of the nurses health study ii. Takkouche b, khudyakov p, costabouzas j, spiegelman d. Donna spiegelman will be presenting her poster power calculations for stepped wedge designs with binary outcomes, in the xxixth international biometric conference poster presentations in barcelona, spain july 25th. Daniel spiegelman software development engineer ii. Childhood maltreatment is an established risk factor for teen pregnancy 14, 15 and is more common among sexual minorities. Aug 29, 2017 objective to investigate the association between lifetime breast feeding, exclusive breast feeding, postpartum amenorrhea, and incidence of endometriosis among parous women. Donna spiegelman harvard university measurement error. According to lellings office, professor donna spiegelman and her team at the chan school overstated how long they spent working on. Chan school of public health donna spiegelman software.
Donna spiegelman scd donna spiegelman is with departments of epidemiology, biostatistics, nutrition, and global health, harvard t. We investigated the association between adulthood weight change and colorectal cancer risk in a prospective study with 24 to 34 years of followup among 90,988 women and 46,679 men. Intensity of smoking was estimated by packs per day and cumulative smoking by packyears. Copyright correspondence can be sent to donna spiegelman, harvard t. Spiegelmans work has revolutionized our views on the control of energy metabolism and on fat tissue, the citation said. Background plantbased diets are recommended for coronary heart disease chd prevention. Correspondence can be sent to donna spiegelman, harvard t. Adulthood weight change and risk of colorectal cancer in the. Plantbased dietary patterns and incidence of type 2 diabetes. Linda spiegelman is 71 years old and was born on 08291948. In this report, we analyzed patterns of sweet taste liking in a pilot study with 26 adults.
Impact of phthalate and bpa exposure during in utero windows. Augmented pseudolikelihood estimation for twophase studies claudia riverarodriguez, sebastien haneuse, molin wang, and donna spiegelman statistical methods in. Such a toolkit might include user friendly software or macros that might allow analysts to. Augmented pseudolikelihood estimation for twophase studies.
Survival analysis with functions of mismeasured covariate histories. As an example, the affordable care act aca has much to offer in terms of support for primary prevention,1,2 and there is much to be learned about the extent to which it has achieved its potential, both in terms of process outcomes i. Results from the european prospective investigation into. Donna spiegelman, departments of epidemiology and biostatistics, harvard school of public health, 677 huntington ave, boston, ma 02115. Prepregnancy dietary protein intake, major dietary protein. Evidence suggests that phthalate and bpa exposure alters steroid hormone levels in adults, while in utero exposure has been associated with altered fetal reproductive development in boys. Incidence of type 2 diabetes mellitus t2dm has reached global epidemic proportions. Methods we included 73,710 women in nhs nurses health study 1984 to 2012, 92,329 women in nhs2 1991 to 20, and 43,259 men. Confidence intervals for heterogeneity measures in metaanalysis. Examples, an evaluation of approximations, and software nicola orsini correspondence to dr. Augmented pseudolikelihood estimation for twophase studies claudia riverarodriguez, sebastien haneuse, molin wang, and donna spiegelman statistical methods in medical research 2019 29.
Evidence suggests that exposure to phthalates and bpa alters reproductive hormone levels in adults 5,6,7,8,9, while exposure during in utero development has been associated with changes in reproductive. Erica provides a holistic approach to helping people overcome their struggles with addictions and dependency and gives them the tools they need to. Metaanalysis for linear and nonlinear doseresponse relations. However, the impact of exposure during distinct critical windows of in utero development on hormone. Valanis, b 1998 correcting for bias in relative risk estimates due to exposure measurement error. Other names that linda uses includes linda r spieglman, linda r spiegelman, linda r speigelman and linda rae spiegelman. Buka, department of community health, brown university, 121 south main street, providence, ri 02912.
Adulthood weight change and risk of colorectal cancer in. Here are some of the people who develop and maintain this software, analyze the data, and design the studies, on the occasion of the celebration of 16 years of working with ellen. Dale barnhart, scd candidate, will be a speaker at the. I also did my phd at karolinska institutet focusing on the development of novel methods for doseresponse metaanalysis, with several applications to lifestyle factors and cancer. Departments of epidemiology, biostatistics, nutrition and global health. Measurement errors in occupational epidemiology donna. Measurement errors in cancer epidemiology donna spiegelman. History of breast feeding and risk of incident endometriosis. Donna spiegelman will be presenting her poster power calculations for stepped wedge designs with binary outcomes, in the xxixth international biometric conference poster presentations in barcelona, spain. Search 45 grants from donna spiegelman search grants from harvard university. Background experiments in animals, international correlation comparisons, and casecontrol studies support an association between dietary fat intake and the incidence of breast cancer. Tetmediated epigenetic regulation in cardiac development. The project described was supported by grant number 5 k23 dk089008.
As hiv is highly prevalent in much of subsaharan africa, it is important to determine risk factors for prematurity among hivpositive pregnancies. Nutritional status and other baseline predictors of. Metaanalysis for linear and nonlinear doseresponse. Classification of these patterns has been somewhat arbitrary. Spiegelman has been awarded multiple designations, distinctions and prestigious honors throughout his career. However, studies regarding the association between dietary protein intake and gestational diabetes mellitus gdm risk are sparse. About erica erica spiegelman is an author, addiction and wellness specialist, and motivational speaker who works with individuals, couples, and families on personal growth and overall wellness. This led to a more than 25year career of independent statistical research on the development of methods for the design and.
He has over 25 years of diverse tax experience including extensive knowledge of alternative investments, partnership taxation and real estate taxation. In the fourminute video, spiegelman, a professor of. Chris spiegelman andersen alternative investment fund. Donna spiegelman professor of epidemiologic methods, emerita department of epidemiology talks 2018. Debashis ghosh awarded the mortimer spiegelman award the. Insulinlike growth factor 1 igf1 is associated with cardiovascular disease, itself a risk factor for hearing impairment, and, in animal studies, molecular evidence suggests a role for igf1 in.